Impact of methodological variables on functional connectivity findings in autism spectrum disorders
نویسندگان
چکیده
منابع مشابه
Impact of methodological variables on functional connectivity findings in autism spectrum disorders.
Growing evidence suggests that Autism Spectrum Disorder (ASD) involves abnormalities of multiple functional networks. Neuroimaging studies of ASD have therefore increasingly focused on connectivity. Many functional connectivity (fcMRI) studies have reported network underconnectivity in children and adults with ASD. However, there are notable inconsistencies, with some studies reporting overconn...
متن کاملHuman Brain Mapping (in press) Impact of methodological variables on functional connectivity findings in autism spectrum disorders
1 Brain Development Imaging Laboratory, Department of Psychology, San Diego State University, San Diego, CA, United States 2 Joint Doctoral Program in Clinical Psychology, San Diego State University and University of California, San Diego, San Diego, CA, United States 3 Department of Cognitive Science, University of California, San Diego, CA 4 Neuroscience Department, Brown University, Providen...
متن کاملAbnormalities of intrinsic functional connectivity in autism spectrum disorders,
Autism spectrum disorders (ASD) impact social functioning and communication, and individuals with these disorders often have restrictive and repetitive behaviors. Accumulating data indicate that ASD is associated with alterations of neural circuitry. Functional MRI (FMRI) studies have focused on connectivity in the context of psychological tasks. However, even in the absence of a task, the brai...
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Ongoing debate exists within the resting-state functional MRI (fMRI) literature over how intrinsic connectivity is altered in the autistic brain, with reports of general over-connectivity, under-connectivity, and/or a combination of both. Classifying autism using brain connectivity is complicated by the heterogeneous nature of the condition, allowing for the possibility of widely variable conne...
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OBJECTIVE Connectivity atypicalities in autism spectrum disorders (ASD) have been extensively proposed. The default mode network (DMN) is critical in this study, given the insight it provides for long-distance connectivity, and the importance of regions in this network for introspection and social emotion processing, areas affected in ASD. However, study of this network has largely been limited...
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ژورنال
عنوان ژورنال: Human Brain Mapping
سال: 2014
ISSN: 1065-9471
DOI: 10.1002/hbm.22456